This gene encodes a phosphoprotein containing six characteristic repeat motifs. The encoded protein binds to the initiator element (Inr) and E-box element in promoters and functions as a regulator of transcription. This locus, along with several other neighboring genes, is deleted in Williams-Beuren syndrome. There are many closely related genes and pseudogenes for this gene on chromosome 7. This gene also has pseudogenes on chromosomes 9, 13, and 21. Alternatively spliced transcript variants encoding multiple isoforms have been observed.

Dettagli prodotto

• Codice: E-AB-13087_20μL
• Marca: Elabscience
• Specie target: Human;Mouse;Rat
• Host: Rabbit
• Concentrazione: 0.6 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: WB;IHC
• Diluizione: WB 1:500-1:2000;IHC 1:50-1:200
• Simbolo target: GTF2I
• Ig target: BAP 135;BAP-135;BAP135;Bruton tyrosine kinase associated protein 135;Bruton tyrosine kinase-associated protein 135;BTK associated protein 135;BTK associated protein 135kD;BTK associated protein;BTK-associated protein 135;BTKAP 1;BTKAP1;DIWS;FLJ38776;FLJ56355;General transcription factor II i;General transcription factor II-I;General transcription factor IIi;GTF 2I;Gtf2i;GTF2I;GTFII I;GTFII-I;IB 291;IB291;SPIN;SRF Phox 1 interacting protein;SRF Phox1 interacting protein;SRF-Phox1-interacting protein;TFII-I;Transcription factor II I;WBS;WBSCR 6;WBSCR6;Williams Beuren syndrome chromosome region 6;Williams Beuren syndrome chromosome region 6 protein;Williams-Beuren syndrome chromosomal region 6 protein
• Area di ricerca: Cancer;Epigenetics and Nuclear Signaling