This gene encodes a member of the NOD (nucleotide-binding oligomerization domain) family. This member is a cytosolic protein. It contains an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling, LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid.

Dettagli prodotto

• Codice: E-AB-13110_120μL
• Marca: Elabscience
• Specie target: Human;Mouse
• Host: Rabbit
• Concentrazione: 0.4 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: IHC
• Diluizione: IHC 1:50-1:200
• Simbolo target: NOD1
• Ig target: CARD 4;CARD4;Caspase recruitment domain 4;Caspase recruitment domain containing protein 4;Caspase recruitment domain family member 4;Caspase recruitment domain protein 4;Caspase recruitment domain-containing protein 4;CLR 7.1;CLR7.1;NLR family CARD domain containing 1;NLRC 1;NLRC1;NOD 1;Nod1;NOD1 protein;NOD1;Nucleotide binding oligomerization domain containing 1;Nucleotide binding oligomerization domain leucine rich repeat and CARD domain containing 1;Nucleotide-binding oligomerization domain-containing protein 1;Protein Nod1
• Area di ricerca: Cancer;Cell Biology