This gene is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has five epidermal growth factor (EGF)-like repeats and one laminin A-G domain. This gene is expressed at high levels in a number of fetal epithelia. Its product probably functions as an adhesion molecule and/or signaling receptor, and is likely to be important in developmental processes and cell communication. Transcript variants derived from alternative splicing and/or alternative promoter usage exist, but they have not been fully described.

Dettagli prodotto

• Codice: E-AB-13237_200μL
• Marca: Elabscience
• Specie target: Human
• Host: Rabbit
• Concentrazione: 0.4 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: IHC
• Diluizione: IHC 1:50-1:200
• Simbolo target: FAT1
• Ig target: Cadherin family member 7;Cadherin family member 7 precursor;Cadherin ME5;Cadherin related tumor suppressor;Cadherin related tumor suppressor homolog;Cadherin related tumor suppressor homolog precursor;Cadherin related tumor suppressor homolog precursor (FAT protein homolog);Cadherin-related tumor suppressor homolog;CDHF 7;CDHF7;FAT 1;FAT tumor suppressor 1;FAT tumor suppressor homolog 1;FAT1;FAT1;hFat 1;hFAT;hFat1;Homolog of Drosophila FAT protein;Homolog of Drosophila FAT protein precursor;Homolog of Drosophila tumor suppressor FAT precursor;ME 5;ME5;nuclear form;Protein fat homolog;Protocadherin Fat 1
• Area di ricerca: Cancer;Cell Biology;Epigenetics and Nuclear Signaling;Signal Transduction