The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains a C-terminal PEST motif, which serves as a protein-protein interaction domain, and may regulate protein intracellular half-life. This PTP was found to bind and dephosphorylate the product of the oncogene c-ABL and thus may play a role in oncogenesis.
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG
Clonalità: Polyclonal
Coniugazione: Unconjugated
Applicazione: WB;IHC
Diluizione: WB 1:200-1:1000;IHC 1:100-1:300
Simbolo target: PTPN12
Ig target: Protein tyrosine phosphatase G1;Protein tyrosine phosphatase non receptor type 12;Protein-tyrosine phosphatase G1;PTN12;PTP PEST;PTP-PEST;PTPG1;Ptpn12;Tyrosine protein phosphatase non receptor type 12;Tyrosine-protein phosphatase non-receptor type 12
Area di ricerca:Cancer;Signal Transduction
Newsletter TEMA RICERCA
Ricevi aggiornamenti rilevanti per il tuo lavoro
Inserisci la tua e-mail e seleziona le aree di interesse per ricevere le ultime novità, approfondimenti e promozioni.