Calpains are a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes. This gene encodes a small subunit common to both calpain I and II and is associated with myotonic dystrophy. Two transcript variants encoding the same protein have been identified for this gene.

Dettagli prodotto

• Codice: E-AB-13959_20μL
• Marca: Elabscience
• Specie target: Human;Mouse;Rat
• Host: Rabbit
• Concentrazione: 0.3 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: WB;IHC
• Diluizione: WB 1:500-1:2000;IHC 1:50-1:200
• Simbolo target: CAPNS1
• Ig target: 30K;Calcium activated neutral proteinase;Calcium activated neutral proteinase small subunit;Calcium dependent protease small subunit 1;Calcium dependent protease small subunit;Calcium-activated neutral proteinase small subunit;Calcium-dependent protease small subunit 1;Calcium-dependent protease small subunit;Calpain 4;Calpain 4 small subunit (30K);Calpain 4 small subunit;Calpain regulatory subunit;Calpain small polypeptide;Calpain small subunit 1;Calpain4;CalpainS1;CANP;CANP small subunit;CANPS;CAPN 4;CAPN S1;CAPN4;CAPNS 1;CAPNS;Capns1;CDPS;CPNS1;CSS 1;CSS1
• Area di ricerca: Cancer;Cell Biology;Metabolism;Signal Transduction