The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy.

Dettagli prodotto

• Codice: E-AB-14059_200μL
• Marca: Elabscience
• Specie target: Human;Mouse
• Host: Rabbit
• Concentrazione: 0.7 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: WB;IHC
• Diluizione: WB 1:500-1:2000;IHC 1:25-1:100
• Simbolo target: ELAVL1
• Ig target: ELAV (embryonic lethal abnormal vision Drosophila) like 1;ELAV (embryonic lethal;abnormal vision;Drosophila) like 1 (Hu antigen R);ELAV like 1;ELAV like RNA binding protein 1;ELAV-like protein 1;ELAV1;ELAV1;Elavl1;Embryonic lethal abnormal vision drosophila homolog like 1;Hu Antigen R;Hu-antigen R;Hua;HuR;MelG
• Area di ricerca: Cancer;Epigenetics and Nuclear Signaling