This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome.

Dettagli prodotto

• Codice: E-AB-14120_60μL
• Marca: Elabscience
• Specie target: Human
• Host: Rabbit
• Concentrazione: 0.2 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: WB;IHC
• Diluizione: WB 1:500-1:2000;IHC 1:50-1:200
• Simbolo target: CFHR1
• Ig target: CFHL;CFHL1;CFHL1P;CFHR1;CFHR1P;Complement factor H related 1;Complement factor H related 1 pseudogene;Complement factor H related protein 1 precursor;Complement factor H-related protein 1;FHR 1;FHR-1;FHR1;FHR1;H factor (complement) like 1;H factor (complement) like 2;H factor like protein 1;H factor-like protein 1;H-factor-like 1;H36 1;H36 2;H36;HFL1;HFL2;MGC104329
• Area di ricerca: Cardiovascular;Immunology