This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response.

Dettagli prodotto

• Codice: E-AB-14170_60μL
• Marca: Elabscience
• Specie target: Human
• Host: Rabbit
• Concentrazione: 0.7 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: IHC
• Diluizione: IHC 1:25-1:100
• Simbolo target: CD85d
• Ig target: CD85 antigen-like family member D;CD85d;CD85d antigen;ILT 4;ILT-4;ILT4;Immunoglobulin like transcript 4;Immunoglobulin-like transcript 4;Leukocyte immunoglobulin like receptor 2;Leukocyte immunoglobulin like receptor subfamily B member 2;Leukocyte immunoglobulin-like receptor 2;Leukocyte immunoglobulin-like receptor subfamily B member 2;Leukocyte immunoglobulin-like receptor;subfamily B (with TM and ITIM domains);member 2;LILRA6;LILRB2;LIR 2;LIR-2;LIR2;LIRb;LIRB2;MIR 10;MIR-10;MIR10;Monocyte/macrophage immunoglobulin like receptor 10;Monocyte/macrophage immunoglobulin-like receptor 10
• Area di ricerca: Immunology