Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells.

Dettagli prodotto

• Codice: E-AB-14248_60μL
• Marca: Elabscience
• Specie target: Human
• Host: Rabbit
• Concentrazione: 0.3 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: IHC
• Diluizione: IHC 1:50-1:200
• Simbolo target: KLRC1
• Ig target: C lectin type II protein;CD159 antigen like family member A;CD159 antigen-like family member A;CD159a;CD159a antigen;Killer cell lectin like receptor subfamily C member 1;KLRC1;MGC13374;MGC59791;Natural killer cell lectin;Natural killer cell protein group 2-A1;Natural killer cell receptor NKG2A;Natural killer group protein 2;NK cell receptor A;NKG2 1/B activating NK receptor;NKG2 A;NKG2 A/B activating NK receptor;NKG2 A/B type II integral membrane protein;NKG2 A/NKG2 B type II integral membrane protein;NKG2;NKG2 B;NKG2-1/B activating NK receptor;NKG2-A/B-activating NK receptor;NKG2-A/NKG2-B type II integral membrane protein;NKG2A;NKG2A;NKG2B;rNKG2A
• Area di ricerca: Cancer;Immunology