This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins witHuman, Mouseono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene.

Dettagli prodotto

• Codice: E-AB-14343_200μL
• Marca: Elabscience
• Specie target: Human;Mouse
• Host: Rabbit
• Concentrazione: 0.2 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: WB;IHC
• Diluizione: WB 1:500-1:2000;IHC 1:15-1:50
• Simbolo target: SIRT3
• Ig target: hSIRT 3;hSIRT3;Mitochondrial nicotinamide adenine dinucleotide dependent deacetylase;NAD dependent deacetylase sirtuin 3 mitochondrial;NAD-dependent protein deacetylase sirtuin-3;mitochondrial;Regulatory protein SIR2 homolog 3;Silent mating type information regulation 2 S.cerevisiae homolog 3;Sir 2 like 3;SIR 2 like protein 3;SIR 3;SIR2 L3;Sir2 like 3;SIR2 like protein 3;SIR2-like protein 3;SIR2L3;SIR3;SIRT 3;SIRT3;Sirtuin 3;Sirtuin silent mating type information regulation 2 homolog 3 (S. cerevisiae);Sirtuin type 3;Sirtuin3
• Area di ricerca: Cancer;Cell Biology;Cardiovascular;Epigenetics and Nuclear Signaling;Metabolism