This gene encodes a HTLV-1 tax1 binding protein. The encoded protein interacts with TNFAIP3, and inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degradation of this protein by caspase-3-like family proteins is associated with apoptosis induced by TNF. This protein may also have a role in the inhibition of inflammatory signaling pathways. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[

Dettagli prodotto

• Codice: E-AB-14418_120μL
• Marca: Elabscience
• Specie target: Human;Mouse;Rat
• Host: Rabbit
• Concentrazione: 0.4 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: IHC
• Diluizione: IHC 1:50-1:200
• Simbolo target: TAX1BP1
• Ig target: 1200003J11Rik;1700069J21Rik;Aa1076;AA930106;CALCOCO 3;CALCOCO3;D6Ertd404e;D6Ertd772e;Human T cell leukemia virus type 1-binding protein;Liver regeneration-related protein LRRG004;MGC94031;PRO0105;T6BP;Tax1 (human T cell leukemia virus type I) binding protein;Tax1 (human T cell leukemia virus type I) binding protein 1;Tax1 binding protein 1;Tax1 binding protein;Tax1-binding protein 1;Tax1-binding protein 1 homolog;TAX1BP1;TAX1BP1 protein;tax1bp1b;TAXB1;TRAF 6 binding protein;TRAF6 binding protein;TRAF6 binding protein T6BP;TRAF6-binding protein;TRAF6-interacting protein;TXBP 151;TXBP151;wu:fc20c12;wu:fc56e11;zgc:73219;zgc:77129
• Area di ricerca: Cancer;Signal Transduction