This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene has a high sequence similarity to the protein encoded by gene ADAMTS16, another family member. It is thought to function as a tumor suppressor. Alternatively spliced transcript variants have been identified, but their biological validity has not been determined.

Dettagli prodotto

• Codice: E-AB-14506_20μL
• Marca: Elabscience
• Specie target: Human;Mouse
• Host: Rabbit
• Concentrazione: 0.2 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: IHC
• Diluizione: IHC 1:50-1:200
• Simbolo target: ADAMTS18
• Ig target: A disintegrin and metalloproteinase with thrombospondin motifs 18;A disintegrin like and metalloprotease (reprolysin type) with thrombospondin type 1 motif 18;A disintegrin like and metalloprotease (reprolysin type) with thrombospondin type 1 motif 21;ADAM metallopeptidase with thrombospondin type 1 motif 18;ADAM-TS 18;ADAM-TS18;ADAMTS 18;ADAMTS-18;ADAMTS18;ADAMTS21;ATS18;Disintegrin and metalloprotease like protein;EC 3.4.24.;KNO2
• Area di ricerca: Cancer;Cell Biology;Signal Transduction