The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene.

Dettagli prodotto

• Codice: E-AB-14592_120μL
• Marca: Elabscience
• Specie target: Human;Mouse;Rat
• Host: Rabbit
• Concentrazione: 0.1 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: WB
• Diluizione: WB 1:200-1:1000
• Simbolo target: NAE1
• Ig target: 59 kDa;A 116A10.1;Amyloid beta precursor protein binding protein 1 59kD;Amyloid beta precursor protein binding protein 1 59kDa;Amyloid beta precursor protein binding protein 1;Amyloid beta precursor protein binding protein 1;59 kDa;Amyloid beta precursor protein-binding protein 1;Amyloid protein binding protein 1;Amyloid protein-binding protein 1;APP BP1;APP-BP1;APPBP 1;APPBP1;HPP 1;HPP1;NAE 1;NAE1;NEDD8 activating enzyme E1 regulatory subunit;NEDD8 activating enzyme E1 subunit 1;NEDD8 activating enzyme E1 subunit;NEDD8-activating enzyme E1 regulatory subunit;Proto oncogene protein 1;Proto-oncogene protein 1;Protooncogene protein 1;ula 1;ULA1
• Area di ricerca: Cell Biology;Epigenetics and Nuclear Signaling