Phosphorylated derivatives of phosphatidylinositol (PtdIns) regulate cytoskeletal functions, membrane trafficking, and receptor signaling by recruiting protein complexes to cell- and endosomal-membranes. Humans have multiple PtdIns proteins that differ by the degree and position of phosphorylation of the inositol ring. This gene encodes an enzyme (PIKfyve; also known as phosphatidylinositol-3-phosphate 5-kinase type III or PIPKIII) that phosphorylates the D-5 position in PtdIns and phosphatidylinositol-3-phosphate (PtdIns3P) to make PtdIns5P and PtdIns(3,5)biphosphate.

Dettagli prodotto

• Codice: E-AB-14682_200μL
• Marca: Elabscience
• Specie target: Human;Mouse
• Host: Rabbit
• Concentrazione: 0.2 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: IHC
• Diluizione: IHC 1:50-1:200
• Simbolo target: PIKFYV
• Ig target: 1 phosphatidylinositol 3 phosphate 5 kinase;1 phosphatidylinositol 4 phosphate 5 kinase;1-phosphatidylinositol 3-phosphate 5-kinase;CFD;epididymis luminal protein 37;FAB1;FAB1;S. cerevisiae;homolog of;FYV1;FYVE finger containing phosphoinositide kinase;FYVE finger-containing phosphoinositide kinase;KIAA0981;MGC40423;p235;Phosphatidylinositol 3 phosphate 5 kinase type III;Phosphatidylinositol 3 phosphate/phosphatidylinositol 5 kinase type III;Phosphatidylinositol 3-phosphate 5-kinase;Phosphatidylinositol 3-phosphate 5-kinase type III;Phosphatidylinositol 4 phosphate 5 kinase type III;Phosphoinositide kinase;FYVE finger containing;PIKfyve;PIP5K;PIP5K3;PIPkin III;PIPkin-III;PtdIns(4)P 5 kinase;Type III PIP kinase;ZFYVE29;Zinc finger;FYVE domain containing 29
• Area di ricerca: Cancer;Metabolism;Signal Transduction