This gene encodes a member of the ankyrin repeat and SOCS box-containing (ASB) protein family. These proteins play a role in protein degradation by coupling suppressor of cytokine signalling (SOCS) proteins with the elongin BC complex. The encoded protein is a subunit of a multimeric E3 ubiquitin ligase complex that mediates the degradation of actin-binding proteins. This gene plays a role in retinoic acid-induced growth inhibition and differentiation of myeloid leukemia cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Dettagli prodotto

• Codice: E-AB-14771_60μL
• Marca: Elabscience
• Specie target: Human;Mouse;Rat
• Host: Rabbit
• Concentrazione: 0.5 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: IHC
• Diluizione: IHC 1:50-1:200
• Simbolo target: ASB2
• Ig target: Ankyrin repeat and SOCS box 2 containing protein;Ankyrin repeat and SOCS box containing 2;Ankyrin repeat and SOCS box containing protein 2;Ankyrin repeat and SOCS box containing protein 2a;Ankyrin repeat and SOCS box protein 2;Ankyrin repeat containing protein ASB2;ASB 2
• Area di ricerca: Cell Biology;Epigenetics and Nuclear Signaling