The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation.

Dettagli prodotto

• Codice: E-AB-14822_120μL
• Marca: Elabscience
• Specie target: Human;Mouse
• Host: Rabbit
• Concentrazione: 0.3 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: IHC
• Diluizione: IHC 1:50-1:200
• Simbolo target: CARD11
• Ig target: 0610008L17Rik;2410011D02Rik;Bcl10 interacting maguk protein 3;BIMP 3;BIMP3;CAR11;CARD 11;CARD containing MAGUK protein 3;Card maguk protein 1;CARD-containing MAGUK protein 1;CARD11;CARD11 protein;Carma 1;CARMA1;Caspase recruitment domain containing protein 11;Caspase recruitment domain family member 11;Caspase recruitment domain-containing protein 11;MGC133069
• Area di ricerca: Cancer;Cell Biology;Epigenetics and Nuclear Signaling;Immunology;Signal Transduction