The B lymphocyte specific CD22 antigen, also designated B-lymphocyte cell adhesion molecule (BLCAM), sialic acid-binding Ig-like lectin 2 (Siglec-2) and Leu-14, is a type I integral membrane glycoprotein, structurally similar to other cell adhesion molecules (CAMs), which acts as a regulator of B cell signaling. CD22 is expressed as both a cytoplasmic and membrane protein during discrete stages of B cell lymphocyte differentiation. The cytoplasmic form of CD22, expressed early in B cell development, is a useful marker for acute lymphocytic leukemia. The membrane form of CD22 is expressed in mature B cells prior to their differentiation into plasma cells.

Dettagli prodotto

• Codice: E-AB-14843_120μL
• Marca: Elabscience
• Specie target: Human
• Host: Rabbit
• Concentrazione: 0.2 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: IHC
• Diluizione: IHC 1:50-1:200
• Simbolo target: CD22
• Ig target: B cell receptor CD22 precursor;B lymphocyte cell adhesion molecule;B-cell receptor CD22;B-lymphocyte cell adhesion molecule;BL CAM;BL-CAM;BLCAM;CD 22;CD22;CD22 antigen;CD22 molecule;CD22 protein;CD22;Lectin 2;Leu14;Lyb8;MGC130020;sialic acid binding Ig like lectin 2;Sialic acid binding immunoglobulin like lectin 2;Sialic acid-binding Ig-like lectin 2;SIGLEC 2;Siglec-2;SIGLEC2;T cell surface antigen Leu 14;T-cell surface antigen Leu-14
• Area di ricerca: Cancer;Immunology;Stem Cells