This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. This protein is thought to have a role in the assembly of extracellular membranes. Also, this gene is down-regulated during transformation of normal myoblasts to rhabdomyosarcoma cells and the encoded protein may function as a link between presenilin-2 and an intracellular signaling pathway. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Dettagli prodotto

• Codice: E-AB-15037_60μL
• Marca: Elabscience
• Specie target: Human;Mouse;Rat
• Host: Rabbit
• Concentrazione: 0.6 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: WB;IHC
• Diluizione: WB 1:1000-1:5000;IHC 1:100-1:300
• Simbolo target: FHL2
• Ig target: AAG 11;AAG11;Aging associated gene 11;Down regulated in rhabdomyosarcoma LIM protein;Downregulated in rhabdomyosarcoma LIM protein;DRAL;FHL 2;FHL-2;Fhl2;FHL2 protein;FHL2;Four and a half LIM domain protein 2;Four and a half LIM domains 2;Four and a half LIM domains protein 2;KIAA0990;LIM domain protein DRAL;Skeletal muscle LIM protein 3;Skeletal muscle LIM-protein 3;SLIM 3;SLIM-3;SLIM3
• Area di ricerca: Cancer;Epigenetics and Nuclear Signaling