The protein encoded by this gene is a member of the CRK-associated substrates family. Members of this family are adhesion docking molecules that mediate protein-protein interactions for signal transduction pathways. This protein is a focal adhesion protein that acts as a scaffold to regulate signaling complexes important in cell attachment, migration and invasion as well as apoptosis and the cell cycle. This protein has also been reported to have a role in cancer metastasis. Alternative splicing results in multiple transcript variants.
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG
Clonalità: Polyclonal
Coniugazione: Unconjugated
Applicazione: WB
Diluizione: WB 1:200-1:1000
Simbolo target: NEDD9
Ig target: Cas like docking;Cas scaffolding protein family member 2;CAS-L;CAS2;CasL;CASL;CASS2;Crk associated substrate related;Crk associated substrate related protein;CRK-associated substrate-related protein;dJ49G10.2 (Enhancer of Filamentation 1 (HEF1));dJ49G10.2;dJ761I2.1 (enhancer of filamentation (HEF1));dJ761I2.1;Enhancer of filamentation 1;Enhancer of filamentation 1 p55;HEF 1;HEF1;NEDD-9;Nedd9;Neural precursor cell expressed developmentally down-regulated protein 9;P105;Renal carcinoma antigen NY-REN-12
Area di ricerca:Cancer;Cell Biology;Epigenetics and Nuclear Signaling;Signal Transduction
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