The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers.

Dettagli prodotto

• Codice: E-AB-15168_120μL
• Marca: Elabscience
• Specie target: Human
• Host: Rabbit
• Concentrazione: 0.4 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: IHC
• Diluizione: IHC 1:50-1:200
• Simbolo target: LDOC1
• Ig target: BCUR1;Breast cancer up regulated 1;Breast cancer upregulated 1;Gm366;Ldoc1;LDOC1;Leucine zipper down regulated in cancer 1;Leucine zipper protein down regulated in cancer cells;Leucine zipper protein down regulated in cancer cells;Leucine zipper protein down-regulated in cancer cells;Mar7;Mart7;Protein LDOC1;RGD1565644
• Area di ricerca: Cancer;Epigenetics and Nuclear Signaling;Signal Transduction