This gene is a candidate tumor suppressor gene which encodes a nuclear RNA binding protein that is a component of the spliceosome A complex. The encoded protein plays a role in the induction of cell cycle arrest and apoptosis through pre-mRNA splicing of multiple target genes including the tumor suppressor protein p53. This gene is located within the tumor suppressor region 3p21.3, and may play a role in the inhibition of tumor transformation and progression of several malignancies including lung cancer.

Dettagli prodotto

• Codice: E-AB-15336_60μL
• Marca: Elabscience
• Specie target: Human;Mouse;Rat
• Host: Rabbit
• Concentrazione: 0.4 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: WB;IHC
• Diluizione: WB 1:500-1:2000;IHC 1:25-1:100
• Simbolo target: RBM5
• Ig target: FLJ39876;G15;H37;LUCA 15;LUCA15;Protein G15;Putative tumor suppressor LUCA15;RBM 5;Rbm5;RBM5;Renal carcinoma antigen NY REN 9;Renal carcinoma antigen NY-REN-9;RMB 5;RMB5;RNA binding motif protein 5;RNA binding protein 5;RNA-binding motif protein 5;RNA-binding protein 5;Tumor suppressor LUCA15
• Area di ricerca: Cancer;Epigenetics and Nuclear Signaling