This gene is a member of the mitochondrial carrier family. The encoded protein contains four EF-hand Ca(2+) binding motifs in the N-terminal domain, and localizes to mitochondria. The protein catalyzes the exchange of aspartate for glutamate and a proton across the inner mitochondrial membrane, and is stimulated by calcium on the external side of the inner mitochondrial membrane. Mutations in this gene result in citrullinemia, type II. Multiple transcript variants encoding different isoforms have been found for this gene.
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG
Clonalità: Polyclonal
Coniugazione: Unconjugated
Applicazione: WB;IHC
Diluizione: WB 1:500-1:2000;IHC 1:25-1:100
Simbolo target: SLC25A13
Ig target: AI785475;ARALAR2;Calcium binding mitochondrial carrier protein Aralar2;Calcium-binding mitochondrial carrier protein Aralar2;Citrin;CMC2;CTLN2;Ctrn;Mitochondrial aspartate glutamate carrier 2;RGD1565889;Slc25a13;Solute carrier family 25 (citrin) member 13;Solute carrier family 25 member 13 (citrin);Solute carrier family 25 member 13
Area di ricerca:Cancer;Metabolism;Neuroscience;Signal Transduction
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