Mucin-5ACis aproteinthat in humans is encoded by theMUC5ACgene. This gene has been linked to mucus hypersecretion in the pulmonary tracts and associated to chronic obstructive pulmonary disease (COPD). Gel-forming glycoprotein of gastric and respiratoy tract epithelia that protects the mucosa from infection and chemical damage by binding to inhaled microrganisms and particles that are subsequently removed by the mucocilary system. Highly expressed in surface mucosal cells of respiratory tract and stomach epithelia. Overexpressed in a number of carcinomas. Also expressed in Barrett's esophagus epithelium and in the proximal duodenum.
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG
Clonalità: Polyclonal
Coniugazione: Unconjugated
Applicazione: IHC
Diluizione: IHC 1:50-1:200
Simbolo target: MUC5AC
Ig target: Apomucin;Apomucin Major Airway Glycoprotein;Gastric mucin;LeB;Lewis B blood group antigen;Major Airway Glycoprotein;MUC 5;MUC5;MUC5AC;Mucin 5 subtype AC tracheobronchial;Mucin 5 Subtypes A And C;Mucin 5 subtypes A and C tracheobronchial/gastric;Mucin 5;tracheobronchial/gastric;Mucin 5AC;Mucin 5AC oligomeric mucus/gel forming;Mucin 5AC;oligomeric mucus/gel forming pseudogene;Mucin;TBM;Tracheobronchial Mucin (TBM);Tracheobronchial mucin
Area di ricerca:Cancer;Immunology;Signal Transduction
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