Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.

Codice: E-AB-15798_120μL | Marca: Elabscience | Confezionamento: 120μL

Specie: Human;Mouse;RatIsotipo: IgGConiugazione: Unconjugated

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Codice: E-AB-15798_120μL
Marca: Elabscience
Specie target: Human;Mouse;Rat
Host: Rabbit
Concentrazione: 0.5 mg/mL
Link: Apri link
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG
Clonalità: Polyclonal
Coniugazione: Unconjugated
Applicazione: IHC
Diluizione: IHC 1:25-1:100
Simbolo target: NBN
Ig target: AT V1;AT V2;ATV;Cell cycle regulatory protein p95;FLJ10155;MGC87362;Nbn;NBN;NBS 1;NBS;NBS1;Nibrin;Nijmegen breakage syndrome 1 (nibrin);Nijmegen breakage syndrome;Nijmegen breakage syndrome protein 1;p95;p95 protein of the MRE11/RAD50 complex
Area di ricerca: Cancer;Epigenetics and Nuclear Signaling

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