This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival.

Dettagli prodotto

• Codice: E-AB-15855_120μL
• Marca: Elabscience
• Specie target: Human;Mouse;Rat
• Host: Rabbit
• Concentrazione: 0.6 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: WB;IHC
• Diluizione: WB 1:500-1:2000;IHC 1:100-1:300
• Simbolo target: SOCS1
• Ig target: CISH 1;CISH1;Cytokine inducible SH2 protein 1;JAB;JAK binding protein;JAK-binding protein;Janus kinase binding protein;SOCS 1;SOCS-1;Socs1;SOCS1;SSI 1;SSI-1;SSI1;STAT induced STAT inhibitor 1;STAT-induced STAT inhibitor 1;Suppressor of cytokine signaling 1;Supressor of cytokine signalling 1;TEC interacting protein 3;Tec-interacting protein 3;TIP 3;TIP-3;TIP3
• Area di ricerca: Cancer;Epigenetics and Nuclear Signaling;Immunology;Signal Transduction