The protein as regulator signaling cascades probably through protein ubiquitination and/or sequestration. It plays an important role in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA.
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG
Clonalità: Polyclonal
Coniugazione: Unconjugated
Applicazione: IHC
Diluizione: IHC 1:50-1:200
Simbolo target: SOCS7
Ig target: Ash and phospholipase C gamma-binding protein;NAP 4;NAP 4 Fragment;NAP-4;NAP4;Nck;Nck Ash and phospholipase C binding protein;Nck Ash and phospholipase C gamma binding protein;Nck associated protein 4;Nck-associated protein 4;NCKAP4;SH2 domain containing SOCS box protein;SOCS 7;SOCS-7;SOCS4;SOCS6;Socs7;SOCS7;Suppressor of cytokine signaling 7
Area di ricerca:Signal Transduction
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