This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina.
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG
Clonalità: Polyclonal
Coniugazione: Unconjugated
Applicazione: IHC
Diluizione: IHC 1:100-1:300
Simbolo target: SFRP1
Ig target: Frizzled related protein 1;FRP 1;FRP;FRP-1;FRP1;FrzA;SARP 2;SARP-2;SARP2;Secreted apoptosis related protein 2;Secreted apoptosis-related protein 2;Secreted frizzled related protein 1;Secreted frizzled related protein;Secreted frizzled-related protein 1;SFRP 1;sFRP-1;SFRP1;SFRP1
Area di ricerca:Cancer;Cell Biology;Developmental Biology;Neuroscience;Stem Cells
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