The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene.

Dettagli prodotto

• Codice: E-AB-16094_60μL
• Marca: Elabscience
• Specie target: Human;Mouse;Rat
• Host: Rabbit
• Concentrazione: 0.3 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: IHC
• Diluizione: IHC 1:100-1:300
• Simbolo target: TGFBR1
• Ig target: AAT 5;AAT5;Activin A receptor type II like kinase 53kDa;Activin A receptor type II like kinase;53kD;Activin A receptor type II like protein kinase of 53kD;activin A receptor type II-like kinase;53kDa;activin A receptor type II-like protein kinase of 53kD;Activin receptor like kinase 5;Activin receptor-like kinase 5;ACVRLK 4;ACVRLK4;ALK 5;ALK-5;ALK5;LDS1A;LDS2A;MSSE;Serine/threonine protein kinase receptor R4;Serine/threonine-protein kinase receptor R4;SKR 4;SKR4;TbetaR I;TbetaR-I;TGF beta receptor type 1;TGF beta receptor type I;TGF beta type I receptor;TGF-beta receptor type I;TGF-beta receptor type-1;TGF-beta type I receptor;TGFBR 1;TGFBR1;TGFBR1 protein;TGFR 1;TGFR-1;TGFR1;TGFR1;Transforming growth factor beta receptor 1;Transforming growth factor beta receptor I (activin A receptor type II like kinase;53kD);Transforming growth factor beta receptor I;transforming growth factor;beta receptor 1;transforming growth factor;beta receptor I (activin A receptor type II-like kinase;53kD);Transforming growth factor-beta receptor type I
• Area di ricerca: Cancer;Cardiovascular;Metabolism;Signal Transduction;Stem Cells