The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. Multiple transcript variants encoding different isoforms have been found for this gene.
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG
Clonalità: Polyclonal
Coniugazione: Unconjugated
Applicazione: IHC
Diluizione: IHC 1:100-1:300
Simbolo target: APBA2
Ig target: Adapter protein X11beta;Amyloid beta A4 precursor protein-binding family A member 2;APBA2;APBA2;D15S1518E;HsT16821;LIN 10;MGC:14091;MGC99508;Mint 2;Mint-2;MINT2;Neuron-specific X11L protein;Neuronal Munc18-1-interacting protein 2;Phosphotyrosine binding/interacting domain (PTB) bearing protein;X11 beta;X11 like protein;X11l
Area di ricerca:Neuroscience
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