Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Transcript variants that encode distinct isoforms have been identified.

Dettagli prodotto

• Codice: E-AB-16183_120μL
• Marca: Elabscience
• Specie target: Human
• Host: Rabbit
• Concentrazione: 0.3 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: WB;IHC
• Diluizione: WB 1:200-1:1000;IHC 1:25-1:100
• Simbolo target: ATG4A
• Ig target: AI627006;APG4 autophagy 4 homolog A;Apg4a;ATG4 autophagy related 4 homolog A (S. cerevisiae);ATG4 autophagy related 4 homolog A;ATG4A;ATG4A;Atg4al;AUT like 2 cysteine endopeptidase;AUT-like 2 cysteine endopeptidase;Autl2;Autophagin 2;Autophagin-2;Autophagy related 4A cysteine peptidase;Autophagy related cysteine endopeptidase 2;Autophagy related protein 4 homolog A;Autophagy-related cysteine endopeptidase 2;Autophagy-related protein 4 homolog A;AV169859;Cysteine protease ATG4A;hAPG4A;MGC107179
• Area di ricerca: Cancer;Cell Biology;Cardiovascular;Metabolism;Signal Transduction