This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. This gene may act as a feedback regulator of caspase-1-dependent interleukin 1-beta secretion. Alternative splicing results in multiple transcript variants encoding different isoforms.

Dettagli prodotto

• Codice: E-AB-16254_60μL
• Marca: Elabscience
• Specie target: Human
• Host: Rabbit
• Concentrazione: 0.5 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: IHC
• Diluizione: IHC 1:100-1:300
• Simbolo target: NLRP7
• Ig target: CLR19.4;FLJ94610;HYDM;MGC126470;MGC126471;NACHT;leucine rich repeat and PYD containing 7;NACHT;LRR and PYD containing protein 7;NACHT;LRR and PYD domains containing protein 7;NACHT;LRR and PYD domains-containing protein 7;NALP7;NALP7;NLR family;pyrin domain containing 7;NLRP7;NOD12;Nucleotide-binding oligomerization domain protein 12;Nucleotide-binding oligomerization domain;leucine rich repeat and pyrin domain containing 7;PAN7;PYPAF3;PYRIN-containing APAF1-like protein 3
• Area di ricerca: Cell biology;Immunology