Bod1, a protein conserved throughout metazoans that associates with a large macromolecular complex and localizes with kinetochores and spindle poles during mitosis.Bod1-depleted cells form syntelic attachments that can oscillate and generate enough force to separate sister kinetochores, suggesting that microtubule-kinetochore interactions were intact. Releasing Bod1-depleted cells from a monastrol block increases the frequency of syntelic attachments and the number of cells displaying biorientation defects.
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG
Clonalità: Polyclonal
Coniugazione: Unconjugated
Applicazione: IHC
Diluizione: IHC 1:50-1:200
Simbolo target: BOD1
Ig target: Biorientation defective 1;Biorientation defective protein 1;biorientation of chromosomes in cell division 1;Biorientation of chromosomes in cell division protein 1;BOD1;BOD1;FAM44B;family with sequence similarity 44;member B;Protein FAM44B
Area di ricerca:Cell biology;Epigenetics and Nuclear Signaling
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