Stable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance. In vertebrates, sister chromatid cohesion is released in 2 steps via distinct mechanisms. The first step involves phosphorylation of STAG1 or STAG2 in the cohesin complex. The second step involves cleavage of the cohesin subunit SCC1 by ESPL1, or separase, which initiates the final separation of sister chromatids.

Codice: E-AB-16415_120μL | Marca: Elabscience | Confezionamento: 120μL

Specie: Human;MouseIsotipo: IgGConiugazione: Unconjugated

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Codice: E-AB-16415_120μL
Marca: Elabscience
Specie target: Human;Mouse
Host: Rabbit
Concentrazione: 1 mg/mL
Link: Apri link
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG
Clonalità: Polyclonal
Coniugazione: Unconjugated
Applicazione: IHC
Diluizione: IHC 1:50-1:200
Simbolo target: ESPL1
Ig target: Caspase like protein ESPL1;Caspase-like protein ESPL1;ESP 1;ESP1;ESPL 1;Espl1;ESPL1;Extra spindle poles like 1;Extra spindle poles like 1 protein;Extra spindle poles-like 1 protein;FLJ46492;KIAA0165;Separase;Separin;Similar to fission yeast cut1and gene;SSE
Area di ricerca: Cancer;Cell biology;Epigenetics and Nuclear Signaling

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