The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation.

Dettagli prodotto

• Codice: E-AB-16508_120μL
• Marca: Elabscience
• Specie target: Human
• Host: Rabbit
• Concentrazione: 0.5 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: IHC
• Diluizione: IHC 1:50-1:200
• Simbolo target: IL12RB2
• Ig target: I12R2;IL-12 receptor subunit beta-2;IL-12R subunit beta-2;IL-12R-beta-2;IL-12RB2;IL12 receptor beta 2;IL12R beta2;IL12RB2;Interleukin 12 receptor beta 2;Interleukin 12 receptor beta 2 chain;Interleukin-12 receptor subunit beta-2;RP11 102M16.1
• Area di ricerca: Cancer;Immunology