NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP4, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes

Dettagli prodotto

• Codice: E-AB-16628_120μL
• Marca: Elabscience
• Specie target: Human
• Host: Rabbit
• Concentrazione: 0.5 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: IHC
• Diluizione: IHC 1:50-1:200
• Simbolo target: NLRP4
• Ig target: Cancer/testis antigen 58;CLR19.5;CT58;FLJ32126;NACHT;leucine rich repeat and PYD containing 4;NACHT;LRR and PYD containing protein 4;NACHT;LRR and PYD domains-containing protein 4;NALP4;NLR family;pyrin domain containing 4;NLRP4;Nucleotide binding oligomerization domain;leucine rich repeat and pyrin domain containing 4;PAAD and NACHT containing protein 2;PAAD and NACHT-containing protein 2;PAN2;PYPAF4;PYRIN and NACHT-containing protein 2;PYRIN containing APAF1 like protein 4;PYRIN-containing APAF1-like protein 4;Ribonuclease inhibitor 2;RNH2
• Area di ricerca: Cell biology;Immunology