The protein encoded by this gene binds arginine-vasopressin and may be involved in the arginine-vasopressin-mediated regulation of renal salt-water balance. The encoded protein also mediates inflammatory responses in the colon to allow recovery from intestinal epithelial damage and protects against tumorigenesis and the development of colitis. Finally, this protein can increase activation of NF-kappa-B, activation of CASP1 through interaction with ASC, and cAMP accumulation. Two transcript variants encoding different isoforms have been found for this gene.

Dettagli prodotto

• Codice: E-AB-16629_200μL
• Marca: Elabscience
• Specie target: Human
• Host: Rabbit
• Concentrazione: 0.6 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: IHC
• Diluizione: IHC 1:50-1:200
• Simbolo target: NLRP6
• Ig target: Angiotensin II/vasopressin receptor;AVR;CLR11.4;NACHT;leucine rich repeat and PYD containing 6;NACHT;LRR and PYD containing protein 6;NACHT;LRR and PYD domains-containing protein 6;NAVR;NAVR/AVR;NLR family;pyrin domain containing 6;Nlrp6;NLRP6;Nucleotide binding oligomerization domain;leucine rich repeat and pyrin domain containing 6;PAN3;PYPAF5;PYRIN containing APAF1 like protein 5;PYRIN-containing APAF1-like protein 5
• Area di ricerca: Cell biology;Immunology;Signal transduction