Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene.
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG
Clonalità: Polyclonal
Coniugazione: Unconjugated
Applicazione: IHC
Diluizione: IHC 1:50-1:200
Simbolo target: NEFH
Ig target: 200 kDa neurofilament protein;CMT2CC;Nefh;Neurofilament heavy polypeptide 200kDa;Neurofilament heavy polypeptide;Neurofilament triplet H protein;NF H;NF-H;NFH;NFH
Area di ricerca:Cancer;Neuroscience;Signal transduction
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