Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1; MIM 184756) and by liver X receptors (e.g., LXRA; MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake.
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG
Clonalità: Polyclonal
Coniugazione: Unconjugated
Applicazione: WB;IHC
Diluizione: WB 1:500-1:2000;IHC 1:40-1:150
Simbolo target: STARD5
Ig target: MGC10327;StAR related lipid transfer protein 5;StAR-related lipid transfer (START) domain containing 5;StARD5;START domain containing 5;START domain containing protein 5
Area di ricerca:Cancer;Cardiovascular;Metabolism;Signal transduction
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