The protein encoded by this gene is a transketolase that acts as a homodimer and catalyzes the conversion of sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate to D-ribose 5-phosphate and D-xylulose 5-phosphate. This reaction links the pentose phosphate pathway with the glycolytic pathway. Variations in this gene may be the cause of Wernicke-Korsakoff syndrome. Three transcript variants encoding different isoforms have been found for this gene.
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG
Clonalità: Polyclonal
Coniugazione: Unconjugated
Applicazione: IHC
Diluizione: IHC 1:30-150
Simbolo target: TKTL1
Ig target: TK 2;TK2;TKR;TKT 2;TKT2;TKTL1;TKTL1;Transketolase 2;Transketolase like 1;Transketolase like protein 1;Transketolase related protein;transketolase-like 1;Transketolase-like protein 1;Transketolase-related protein;Transketolase2
Area di ricerca:Cancer;Metabolism;Signal transduction
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