This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6.

Dettagli prodotto

• Codice: E-AB-17100_120μL
• Marca: Elabscience
• Specie target: Human;Mouse
• Host: Rabbit
• Concentrazione: 0.7 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: IHC
• Diluizione: IHC 1:30-150
• Simbolo target: FUS
• Ig target: 75 kDa DNA pairing protein;75 kDa DNA-pairing protein;ALS6;Amyotrophic lateral sclerosis 6;fus;FUS CHOP;Fus like protein;FUS;FUS1;Fused in sarcoma;Fusion (involved in t(12;16) in malignant liposarcoma);Fusion derived from t(12;16) malignant liposarcoma;Fusion gene in myxoid liposarcoma;Heterogeneous nuclear ribonucleoprotein P2;hnRNP P2;hnRNPP2;Oncogene FUS;Oncogene TLS;POMp75;RNA binding protein FUS;RNA-binding protein FUS;TLS;TLS CHOP;Translocated in liposarcoma;Translocated in liposarcoma protein
• Area di ricerca: Cancer;Epigenetics and Nuclear Signaling;Signal transduction