Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1 (By similarity).

Codice: E-AB-17184_120μL | Marca: Elabscience | Confezionamento: 120μL

Specie: Human;MouseIsotipo: IgGConiugazione: Unconjugated

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Codice: E-AB-17184_120μL
Marca: Elabscience
Specie target: Human;Mouse
Host: Rabbit
Concentrazione: 0.8 mg/mL
Link: Apri link
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG
Clonalità: Polyclonal
Coniugazione: Unconjugated
Applicazione: IHC
Diluizione: IHC 1:30-150
Simbolo target: UACA
Ig target: FLJ10128;KIAA1561;MGC141967;MGC141969;Nuclear membrane binding protein;NUCLING;UACA;UACA;Uveal autoantigen with coiled coil domains and ankyrin repeats;Uveal autoantigen with coiled-coil domains and ankyrin repeats
Area di ricerca: Cell biology;Immunology

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