This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death.

Codice: E-AB-17625_20μL | Marca: Elabscience | Confezionamento: 20μL

Specie: Human;MouseIsotipo: IgGConiugazione: Unconjugated

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Codice: E-AB-17625_20μL
Marca: Elabscience
Specie target: Human;Mouse
Host: Rabbit
Concentrazione: 0.4 mg/mL
Link: Apri link
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG
Clonalità: Polyclonal
Coniugazione: Unconjugated
Applicazione: IHC
Diluizione: IHC 1:20-100
Simbolo target: SLC7A11
Ig target: Amino acid transport system xc xCT;Amino acid transport system xc-;Calcium channel blocker resistance protein CCBR1;Calcium channel blocker resistance protein CCBR1;CCBR1;Cysteine/glutamate transporter;Cystine/glutamate transporter;OTTHUMP00000164578;SLC7A11;Solute carrier family 7 (anionic amino acid transporter light chain;xc- system);member 11;solute carrier family 7;Solute carrier family 7 member 11;Solute carrier family 7;(cationic amino acid transporter;y+ system) member 11;SYSTEM Xc(-) TRANSPORTER-RELATED PROTEIN;xCT;XCT
Area di ricerca: Cancer;Cell biology;Metabolism;Signal transduction

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