The protein encoded by this gene is a member of the Serine/Threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described, and the full-length nature of two of them has been reported.

Dettagli prodotto

• Codice: E-AB-17780_200μL
• Marca: Elabscience
• Specie target: Human;Mouse;Rat
• Host: Rabbit
• Concentrazione: 0.8 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: IHC
• Diluizione: IHC 1:40-1:200
• Simbolo target: CDC42BPA
• Ig target: A930014J19Rik;CDC42 binding protein kinase alpha (DMPK like);CDC42 binding protein kinase alpha;CDC42 binding protein kinase alpha dmpk like;CDC42 binding protein kinase beta;CDC42-binding protein kinase alpha;CDC42BPA;DKFZp686L1738;DKFZp686P1738;DMPK like;DMPK-like alpha;FLJ23347;KIAA0451;MGC189823;MRCK alpha;mrck;mrcka;MRCKA;Myotonic dystrophy kinase related CDC42 binding protein kinase alpha;Myotonic dystrophy kinase-related CDC42-binding kinase alpha;Myotonic dystrophy protein kinase-like alpha;OTTHUMP00000035727;OTTHUMP00000035728;OTTHUMP00000035729;OTTHUMP00000035730;pk428;RP5-1087E8.4;Ser thr protein kinase PK428;Ser thr protein kinase related to the myotonic dystrophy protein kinase;Serine/threonine protein kinase MRCK alpha;Serine/threonine-protein kinase MRCK alpha
• Area di ricerca: Cancer;Signal Transduction