Plays a role in DNA repair through recruitment of the FA core complex to damaged DNA. Regulates FANCD2 monoubiquitination upon DNA damage. Induces chromosomal instability as well as hypersensitivity to DNA cross-linking agents, when repressed. Targets FANCM/FAAP24 complex to the DNA, preferentially to single strand DNA.

Codice: E-AB-17929_120μL | Marca: Elabscience | Confezionamento: 120μL

Specie: Human;MouseIsotipo: IgGConiugazione: Unconjugated

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Codice: E-AB-17929_120μL
Marca: Elabscience
Specie target: Human;Mouse
Host: Rabbit
Concentrazione: 0.84 mg/mL
Link: Apri link
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG
Clonalità: Polyclonal
Coniugazione: Unconjugated
Applicazione: IHC
Diluizione: IHC 1:30-1:150
Simbolo target: FAAP24
Ig target: C19ORF40;C19orf40 chromosome 19 open reading frame 40;FAAP24;Fanconi anemia-associated protein 24 kDa;Fanconi anemia-associated protein of 24 kDa;FAP24;MGC32020
Area di ricerca: Epigenetics and Nuclear Signaling

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