This gene encodes a phosphoprotein that binds to the Na+/H+ exchanger NHE1. This protein serves as an essential cofactor which supports the physiological activity of NHE family members and may play a role in the mitogenic regulation of NHE1. The protein shares similarity with calcineurin B and calmodulin and it is also known to be an endogenous inhibitor of calcineurin activity.CHP1 (Calcineurin Like EF-Hand Protein 1) is a Protein Coding gene. Among its related pathways are Role of Calcineurin-dependent NFAT signaling in lymphocytes and Calcineurin-regulated NFAT-dependent transcription in lymphocytes. GO annotations related to this gene include calcium ion binding and microtubule binding. An important paralog of this gene is CHP2.
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG
Clonalità: Polyclonal
Coniugazione: Unconjugated
Applicazione: IHC
Diluizione: IHC 1:30-1:150
Simbolo target: CHP1
Ig target: Calcineurin B homolog;Calcineurin B homologous protein;Calcineurin homologous protein;Calcineurin like EF hand protein 1;Calcium binding protein CHP;Calcium binding protein p22;Calcium-binding protein CHP;Calcium-binding protein p22;chp;CHP1;Sid 470;Sid470;SLC9A1 binding protein;SLC9A1BP;Wrch2
Area di ricerca:Cancer;Metabolism;Signal Transduction
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