Human major histocompatibility complex (MHC) antigens,also referred to as human leukocyte antigens (HLA),are encoded by genes located on the short arm of chromosome 6 (6p21.3). HLA-G is a non-classical MHC class I molecule with multiple immunoregulatory properties. HLA-G exhibits a restricted pattern of expression that includes placental extravillous trophoblasts at the maternal-fetal interface,where it abolishes maternal immune cell activity against fetus and establishes immune tolerance. Aberrant expression of HLA-G has been found in a variety of human neoplastic diseases. It plays an important role in the escape of tumor cells from immunosurveillance.

Dettagli prodotto

• Codice: E-AB-18031_200μL
• Marca: Elabscience
• Specie target: Human
• Host: Rabbit
• Concentrazione: 1.26 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: IHC
• Diluizione: IHC 1:50-1:300
• Simbolo target: HLA-G
• Ig target: B2 microglobulin;DADB-15K14.8;HLA 6.0;HLA class I histocompatibility antigen alpha chain G;HLA class I histocompatibility antigen;alpha chain G;HLA class I molecule;HLA G;HLA G antigen;HLA G histocompatibility antigen class I G;HLA G3;HLA-G;HLA-G histocompatibility antigen;class I;HLA60;HLAG;HLAG;Major histocompatibility complex class I G;MHC class I antigen;MHC class I antigen G;MHC G;T-cell A locus;TCA
• Area di ricerca: Cancer;Immunology