Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520). The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events (PubMed:8182049, PubMed:7622471, PubMed:9553099). Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production (PubMed:10636859, PubMed:15153520).

Dettagli prodotto

• Codice: E-AB-18573_200μL
• Marca: Elabscience
• Specie target: Human
• Host: Rabbit
• Concentrazione: 0.7 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: IHC
• Diluizione: IHC 1:40-1:200
• Simbolo target: C5AR1
• Ig target: ANAPHYLATOXIN RECEPTOR;C5a anaphylatoxin chemotactic receptor;C5a anaphylatoxin receptor;C5A;C5a ligand;C5a-R;C5aR;C5AR;c5ar1;C5R1;CD88;CD88 antigen;Complement component 5 receptor 1;Complement component 5 receptor 2;Complement component 5a receptor 1
• Area di ricerca: Cancer;Metabolism;Immunology;Signal Transduction