Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1B, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2; see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery.

Codice: E-AB-18656_200μL | Marca: Elabscience | Confezionamento: 200μL

Specie: Human;MouseIsotipo: IgGConiugazione: Unconjugated

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Codice: E-AB-18656_200μL
Marca: Elabscience
Specie target: Human;Mouse
Host: Rabbit
Concentrazione: 0.54 mg/mL
Link: Apri link
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG
Clonalità: Polyclonal
Coniugazione: Unconjugated
Applicazione: WB
Diluizione: WB 1:500-1:2000
Simbolo target: DENND1B
Ig target: C1ORF18;C1orf218 ;Chromosome 1 open reading frame 218;Connecdenn 2;DEN1B;DENN domain containing protein 1B;DENN domain-containing protein 1B;DENN MADD domain containing 1B;DENND1B;DKFZp547O0715;FAM31B ;Family with sequence similarity 31 member B;FLJ20054;FLJ21179 ;FLJ33888;MGC103810;MGC27044;Protein FAM31B;RP11 53I24.2
Area di ricerca: Cell Biology

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