TP63,also named KET,P63,P73H,P73L and TP73L,belongs to the p53 family. It is a homologue of the tumor suppressor p53 and p73 genes. It is involved in malignancy acquisition and maintenance of cells. Unlike p53,the p63 gene encodes multiple isotypes with remarkably divergent abilities to transactivate p53 reporter genes and induce apoptosis. TP63 acts as a sequence specific DNA binding transcriptional activator or repressor. TP63 has 12 isoforms with MW 40kd(P40),50kd(P60),63kd(P63) and 73kd(P73L). It is Nuclear stain.

Dettagli prodotto

• Codice: E-AB-18722_200μL
• Marca: Elabscience
• Specie target: Human;Mouse;Rat
• Host: Rabbit
• Concentrazione: 1.14 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: IHC
• Diluizione: IHC 1:50-1:200
• Simbolo target: TP63
• Ig target: AIS;Amplified in squamous cell carcinoma;B(p51A);B(p51B);Chronic ulcerative stomatitis protein;CUSP;DN p63 alpha 1;DNp63;EEC3;id:ibd3516;Keratinocyte transcription factor;Keratinocyte transcription factor KET;KET;LMS;MGC115972;MGC192897;NBP;OFC8;OTTHUMP00000209732;OTTHUMP00000209733;OTTHUMP00000209734;OTTHUMP00000209735;OTTHUMP00000209737;OTTHUMP00000209738;OTTHUMP00000209739;OTTHUMP00000209740;OTTHUMP00000209741;OTTHUMP00000209742;OTTHUMP00000209743;OTTHUMP00000209744;p40;p51;P51/P63;p53-related protein p63;p53CP;p63;P63;p73H;p73L;RHS;SHFM4;TAp63alpha;TP53CP;TP53L;TP63;TP73L;Transformation related protein 63;Transformation-related protein 63;Trp53rp1;Trp63;Tumor protein 63;Tumor protein p53-competing protein;Tumor protein p53-like;Tumor protein p63;Tumor protein p63 deltaN isoform delta;Tumor protein p73;Tumor protein p73-like
• Area di ricerca: Cancer;Cell Biology;Epigenetics and Nuclear Signaling