This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 5 WD repeats, and has a structural similarity with actin-binding proteins: the D. discoideum coronin and the human p57 protein, suggesting that this protein may also be an actin-binding protein that regulates cell motility. Alternative splicing of this gene generates 2 transcript variants.
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG
Clonalità: Polyclonal
Coniugazione: Unconjugated
Applicazione: IHC
Diluizione: IHC 1:40-1:200
Simbolo target: CORO2A
Ig target: CLIPINB;COR2A;CORO 2A;CORO2A;Coronin 2A;Coronin actin binding protein 2A;Coronin like protein B;Coronin-2A;DKFZp686G19226;IR10;OTTHUMP00000021767;OTTHUMP00000021768;WD protein IR10;WD repeat containing protein 2;WD repeat protein 2;WD repeat-containing protein 2;WDR2
Area di ricerca:Epigenetics and Nuclear Signaling;Signal transduction
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